Extracellular RNA Biomarkers of Duchenne Muscular Dystrophy

Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY

Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in finding less invasive methods that reduce the need for muscle biopsies. The purpose of this research is to learn about the possibility of detecting and measuring the activity and severity of muscular dystrophies by examining a urine sample and a blood sample.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 5
View:

• Subjects with DMD or BMD based on genetic testing. Control subjects are unknown to have any other muscular dystrophy by history and may have had no genetic testing.

• Able to provide informed consent or assent for participation in the study.

• Demographic characteristics for biofluid collection: Males age 5 years and older with DMD or BMD; males and females ages 18 years and older without muscular dystrophy.

Locations
United States
Massachusetts
Boston Children's Hospital
ACTIVE_NOT_RECRUITING
Boston
Massachusetts General Hospital
RECRUITING
Boston
Contact Information
Primary
Tamkin Shahraki, MD
tshahraki@mgh.harvard.edu
617-726-7506
Time Frame
Start Date: 2019-11-30
Estimated Completion Date: 2027-11
Participants
Target number of participants: 100
Treatments
Biofluid collection
Eligible volunteers will be asked to provide a single urine sample and undergo a single blood draw.
Sponsors
Collaborators: Boston Children's Hospital
Leads: Massachusetts General Hospital

This content was sourced from clinicaltrials.gov